Sr. Principal Engineer, Clinical Data Platforms

Job Description General Summary: We are seeking a unique leader with a passion for data and technology – responsible for leading and managing our growing delivery & operations team that manage and enable Vertex’s Clinical Data Standards & Electronic Data Capture (EDC) solutions enterprise wide. As part of the Data & Software Engineering Team (DSE) you will enable our Clinical Data Management & Study Teams with accurate and secure information to analyze trials using our centralized platform. Vertex Pharmaceuticals is in a transformational period where we are accelerating our capabilities, technologies, and data to augment our scientific mission, enable Vertex to grow in scale, and continue to be on the forefront of science, medicine, and technology. As part of this effort, it is critical that users have data “at their fingertips” with a strong platform team to build and enable additional value. The Associate Director | Clinical Data Platform will be a key member of the Data Platforms team, driving forward delivery & operations teams, and maximizing business value for Vertex. You will be responsible for managing a team of operations leads, engineers, and consultants who build, enhance, and manage critical Clinical data solutions across the enterprise. You will engage with IT teams to improve our existing data solutions and drive increased value with our Clinical Data Standards Platform (CDSP) and our EDC capabilities. You will work in partnership with the Director | Data Platforms to architect sound solutions, secure data, deliver continuous value, standardize our solutions, and advance our data platform. You will play a key role in the Vertex story. Key Responsibilities: Delivery management – Estimate, architect, and execute on the delivery of critical clinical data solutions across the enterprise in partnership with the DSE leadership team Operations Management – Lead a comprehensive, global team of engineers and consultant teams to deliver value and manage Vertex’s CDSP and EDC technologies Business Engagement – partner with and enable the Clinical Data Management, Quality, Regulatory, & Study execution teams to deliver on prioritized outcomes Application & solution management – Own, operate, and manage GCP data and analytics solutions in alignment with SOPs and industry best practices Team management - Lead and mentor a high performing team of employees and contractors to deliver predictable value with quality and agility Technology champion – Advocate for automation, security, compliance and standards across the Clinical Data Management space Innovation champion - Advocate for process enhancements and opportunities to improve our data & analytics capabilities with a focus on modern data engineering capabilities and approaches Qualifications: Successful track record working with Clinical Data Platforms & Clinical Trial Data Successful track record managing an integrated vendor team, supporting an organization 24/7/365 Demonstrated experience working with GxP solutions in the Clinical Trials environment Experience in delivery in agile environments (5+ years) Demonstrated ability to work independently and manage multiple projects that require collaboration across clinical areas Skillful, collaborative team player able to develop rapport and credibility with stakeholders Demonstrated ability and willingness to teach, engage and support others as they learn new technologies and concepts Enthusiasm for and the ability to quickly learn new technologies and tackle difficult problems An understanding of enterprise software development tools and methodologies Strong presentation, verbal, and written communication skills Strong understanding of FDA, ICH, & CDISC regulations and industry standards Strong understanding of Clinical platforms including Veeva CDMS, and Elluminate and the management of a technology ecosystem High level of comfort sourcing, manipulating, and visualizing clinical data and providing contextualized data to business teams Demonstrated understanding and experience with authoring, developing, and maintaining SOPs for Clinical applications Education and Experience: Bachelor's degree in technology discipline or equivalent Typically requires 8 years relevant business systems in the Life Sciences industry, or the equivalent combination of education and experience Pay Range: $165,600 - $248,400 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: Remote-Eligible Flex Eligibility Status: In this Remote-Eligible role, you can choose to be designated as: 1. Remote: work remotely five days per week and come into the office on occasion – you’re always welcome on-site; or select 2. Hybrid: work remotely up to two days per week; or select 3. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time. Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com Help Us Achieve Our Mission Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases. The company has approved medicines that treat the underlying causes of multiple chronic, life-shortening genetic diseases — cystic fibrosis, sickle cell disease and transfusion-dependent beta thalassemia — and continues to advance clinical and research programs in these diseases. Vertex also has a robust clinical pipeline of investigational therapies across a range of modalities in other serious diseases where it has deep insight into causal human biology, including APOL1-mediated kidney disease, acute and neuropathic pain, type 1 diabetes, myotonic dystrophy type 1 and alpha-1 antitrypsin deficiency . Founded in 1989 in Cambridge, Mass., Vertex's global headquarters is now located in Boston's Innovation District and its international headquarters is in London. Additionally, the company has research and development sites and commercial offices in North America, Europe, Australia, Latin America and the Middle East. Vertex is consistently recognized as one of the industry's top places to work, including 14 consecutive years on Science magazine's Top Employers list and one of Fortune’s 100 Best Companies to Work For. For company updates and to learn more about Vertex's history of innovation, visit www.vrtx.com or follow us on Facebook, Twitter/X , LinkedIn, YouTube and Instagram. The diversity and authenticity of our people is part of what makes Vertex unique, and we recognize that each employee brings diverse perspectives and strengths. By embracing those strengths and celebrating differences, we are fostering an inclusive culture where each of us can bring our authentic selves to work, inspire innovation together, and change people’s lives. Our vision is clear: to be the place where an authentic, diverse mix of talent want to come, to stay, and do their best work.